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Article

Polymorphisms of the human hexokinase II gene: lack of association with NIDDM and insulin resistance.

Diabetologia - 1 May 1995

Laakso M, Malkki M, Kekäläinen P, Kuusisto J, Deeb S S

Abstract excerpt

Skeletal muscle and adipose tissue hexokinase II is a promising candidate gene for non-insulin-dependent diabetes mellitus (NIDDM) and insulin resistance. Therefore, we investigated the association of alleles at four polymorphic loci in this gene with NIDDM and insulin resistance in 110 Finnish diabetic patients with NIDDM and in 97 Finnish control subjects with normal glucose tolerance and a negative family...

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PMID: 7489847
DOI: 10.1007/BF00400733

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Polymorphisms of the human hexokinase II gene: lack of association with NIDDM and insulin resistance.PMID 7489847Read ↗

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Human hexokinase II gene: exon-intron organization, mutation screening in NIDDM, and its relationship to muscle hexokinase activity.Semantic proximity Read ↗

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Identification of four amino acid substitutions in hexokinase II and studies of relationships to NIDDM, glucose effectiveness, and insulin sensitivity.Semantic proximity Read ↗

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