Article
Analysis of the thermodynamic linkage of DNA binding and ion binding for dimeric and tetrameric forms of the lac repressor.
European journal of biochemistry - 15 Dec 1994
Stickle D F, Liu G, Fried M G
Abstract excerpt
The salt concentration dependences of the observed association constants (Kobs) for the binding of wild-type lac repressor tetramer and the dimeric lacI-18 mutant repressor to lactose operator DNA were compared. For both proteins, the data are consistent with a class of linkage models in which io...
Topics
- Anions
- Cations
- DNA
- Gene Deletion
- Lac Operon
- Macromolecular Substances
- Mutation
- Potassium Chloride
- Repressor Proteins
- Thermodynamics