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Insulin resistance and cancer: the role of insulin and IGFs

3 Dec 2012

Abstract excerpt

Insulin, IGF1, and IGF2 are the most studied insulin-like peptides (ILPs). These are evolutionary conserved factors well known as key regulators of energy metabolism and growth, with crucial roles in insulin resistance-related metabolic disorders such as obesity, diseases like type 2 diabetes mellitus, as well as associated immune deregulations. A growing body of evidence suggests that insulin and IGF1 receptors...

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Share to Cancer, Hypoxia, and Metabolism
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PMID: 23207292
DOI: 10.1530/erc-12-0324

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