Article
Heterologous strain challenge of cattle immunized with Anaplasma marginale outer membranes.
Veterinary immunology and immunopathology - 1 Sept 1994
Palmer G H, Munodzana D, Tebele N, Ushe T, McElwain T F
Abstract excerpt
In this study, we tested the hypothesis that outer membrane immunization would induce protection against an antigenically variant strain. Outer membranes were isolated from the Virginia strain of Anaplasma marginale using density gradient centrifugation, combined with saponin adjuvant, and used to immunize Friesian cattle in Zimbabwe. Immunized cattle developed high antibody titers (80,000-160,000) against outer...
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