Article
Anaplasma marginale type IV secretion system proteins VirB2, VirB7, VirB11, and VirD4 are immunogenic components of a protective bacterial membrane vaccine.
Infection and immunity - 1 Mar 2010
Sutten Eric L, Norimine Junzo, Beare Paul A, Heinzen Robert A, Lopez Job E, Morse Kaitlyn, Brayton Kelly A, Gillespie Joseph J, Brown Wendy C
Abstract excerpt
Anaplasma and related Ehrlichia spp. are important tick-borne, Gram-negative bacterial pathogens of livestock and humans that cause acute infection and disease and can persist. Immunization of cattle with an Anaplasma marginale fraction enriched in outer membranes (OM) can provide complete protection against disease and persistent infection. Serological responses of OM vaccinees to the OM proteome previously...
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