Immunogenicity of <i>Anaplasma marginale</i> Type IV Secretion System Proteins in a Protective Outer Membrane Vaccine

doi:10.1128/iai.00061-07

Article

Immunogenicity of <i>Anaplasma marginale</i> Type IV Secretion System Proteins in a Protective Outer Membrane Vaccine

6 Mar 2007

Abstract excerpt

Rickettsial pathogens in the genera Anaplasma and Ehrlichia cause acute infection in immunologically naive hosts and are major causes of tick-borne disease in animals and humans. Immunization with purified outer membranes induces protection against acute Anaplasma marginale infection and disease, and a proteomic and genomic approach recently identified 21 proteins within the outer membrane immunogen in addition...

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