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Targeted mutagenesis in Anaplasma marginale to define virulence and vaccine development against bovine anaplasmosis

16 May 2022

Abstract excerpt

Tick-borne Anaplasma species are obligate, intracellular, bacterial pathogens that cause important diseases globally in people, agricultural animals, and dogs. Targeted mutagenesis methods are yet to be developed to define genes essential for these pathogens. In addition, vaccines conferring protection against diseases caused by Anaplasma species are not available. Here, we describe a targeted mutagenesis method...

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PMID: 35576225
DOI: 10.1371/journal.ppat.1010540

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