Article
Observations on the levels of Hb A2 in patients with different beta-thalassemia mutations and a delta chain variant.
Blood - 15 Sept 1990
Codrington J F, Li H W, Kutlar F, Gu L H, Ramachandran M, Huisman T H
Abstract excerpt
Hb A2 and its variant B2 (alpha 2 delta 2(16)(A13)Gly----Arg) were quantitated in the blood of subjects with three different types of beta-thalassemia and with the delta-B2 anomaly in cis or in trans to the beta-thalassemia determinant. In one family, the delta-B2 mutation was in cis to a newly d...
Topics
- Adolescent
- Adult
- Base Sequence
- Beta-Globulins
- Child
- Female
- Gene Frequency
- Genetic Variation
- Hemoglobin A
- Hemoglobin A2
- Hemoglobins
- Heterozygote
- Humans