Genotypic diversity of reassortants between simian rotavirus SA11 and human rotaviruses having different antigenic specificities and RNA patterns.

doi:10.1016/s0923-2516(07)80035-5

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Article

Genotypic diversity of reassortants between simian rotavirus SA11 and human rotaviruses having different antigenic specificities and RNA patterns.

Research in virology - 1 Jan 2000

Kobayashi N, Kojima K, Taniguchi K, Urasawa T, Urasawa S

Abstract excerpt

A total of 200 clones of reassortants were generated in vitro between simian rotavirus SA11 (SA11-L2 strain) and each of five human rotavirus (HRV) strains with different antigenic specificities and RNA patterns. When culture fluid coinfected with parent viruses was subjected to repeated selection with anti-HRV-VP4 and anti-SA11-VP7 neutralizing monoclonal antibodies, all yielded progenies were antigenic mosaic...

Topics

Animals
Antibodies, Monoclonal
Antibodies, Viral
Antigens, Viral
Capsid
Capsid Proteins
Cell Line
Enzyme-Linked Immunosorbent Assay
Genetic Variation
Genotype
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Macaca mulatta

RNA, Double-Stranded

RNA, Viral

Recombination, Genetic

Rotavirus

Selection, Genetic

Species Specificity

Source

Open in PubMed

Identifiers

PMID: 7839008
DOI: 10.1016/s0923-2516(07)80035-5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7839008-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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