Article
Invasive chronic inflammatory monocyte phenotype in subjects with high HIV-1 viral load.
Journal of neuroimmunology - 1 Dec 2004
Pulliam Lynn, Sun Bing, Rempel Hans
Abstract excerpt
Human immunodeficiency virus type 1 (HIV-1)-infected monocytes trafficking into the central nervous system are a risk factor for HIV-1-associated dementia. We performed global gene expression analysis on CD14+ monocytes isolated from HIV-1-infected individuals and controls to identify HIV-1-related changes in monocyte phenotype. Monocytes from subjects with high viral load (HVL) had a significant increase in...
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