Article
Lysine-based structure in the proregion of procathepsin L is the recognition site for mannose phosphorylation.
The Journal of biological chemistry - 30 Jun 1995
Cuozzo J W, Tao K, Wu Q L, Young W, Sahagian G G
Abstract excerpt
The recognition of lysosomal enzymes by UDP-GlcNAc: lysosomal-enzyme GlcNAc-1-phosphotransferase (phosphotransferase) is mediated by a protein structure on lysosomal enzymes. It has been previously demonstrated that lysine residues are required for phosphorylation of procathepsin L and are a comm...
Topics
- 3T3 Cells
- Animals
- Cathepsin D
- Cathepsin L
- Cathepsins
- Enzyme Precursors
- Hydrogen-Ion Concentration
- Lysine
- Mannose
- Mice
- Mutation
- Phosphorylation