Article
Molecular basis for protein C hereditary deficiency.
Haemostasis - 1 Oct 1996
Aiach M, Gandrille S
Abstract excerpt
The clinical presentation of hereditary protein C deficiency is highly variable. Homozygosity and compound heterozygosity have been linked to severe thrombotic complications early in the life. Heterozygous patients have a moderate form of the disease with deep venous thrombosis during adulthood....
Topics
- Alleles
- DNA Mutational Analysis
- Disease Susceptibility
- Factor V
- Factor V Deficiency
- France
- Genes
- Genotype
- Humans
- Protein C
- Protein C Deficiency
- Protein Structure, Tertiary
- Thromboembolism