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Article

Altered insulin secretory responses to glucose in subjects with a mutation in the MODY1 gene on chromosome 20.

Diabetes - 1 Jun 1995

Byrne M M, Sturis J, Fajans S S, Ortiz F J, Stoltz A, Stoffel M, Smith M J, Bell G I, Halter J B, Polonsky K S

Abstract excerpt

This study was undertaken to test the hypothesis that the diabetes susceptibility gene on chromosome 20q12 responsible for maturity-onset diabetes of the young (MODY) in a large kindred, the RW family, results in characteristic alterations in the dose-response relationships between plasma glucose concentration and insulin secretion rate (ISR) that differentiate this form of MODY from MODY in subjects with...

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Identifiers

PMID: 7789636
DOI: 10.2337/diab.44.6.699

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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