[Diabetes mellitus and molecular biology].

Abstract excerpt

There are two approaches to identify diabetes-susceptibility genes. One approach is to isolate and characterize genes expressed in the beta-cell and in insulin target tissues whose mutation or altered expression may contribute to the development of diabetes mellitus. Another approach is to clone a diabetes-susceptibility gene by a reverse genetic strategy. The first step for this strategy is to identify a DNA...

Topics

• Diabetes Mellitus
• Genes
• Humans
• Insulin
• Mutation
• Receptor, Insulin