Effects of phleomycin-induced DNA damage on the fission yeast Schizosaccharomyces pombe cell cycle.

doi:10.1002/yea.320110305

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Article

Effects of phleomycin-induced DNA damage on the fission yeast Schizosaccharomyces pombe cell cycle.

Yeast (Chichester, England) - 1 Mar 1995

Belenguer P, Oustrin M L, Tiraby G, Ducommun B

Abstract excerpt

The effect of phleomycin, a bleomycin-like antibiotic, has been investigated in the fission yeast, Schizosaccharomyces pombe. We report that in response to phleomycin-induced DNA damage, growth was inhibited and S. pombe cells arrested in the G2-phase of the cell cycle. DNA repair mutants rad9 an...

Topics

Cell Cycle
Cell Division
DNA Damage
DNA Repair
DNA, Fungal
Drug Resistance, Microbial
G2 Phase
Models, Biological
Mutation
Phleomycins
Schizosaccharomyces

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