Article
Effects of phleomycin-induced DNA damage on the fission yeast Schizosaccharomyces pombe cell cycle.
Yeast (Chichester, England) - 1 Mar 1995
Belenguer P, Oustrin M L, Tiraby G, Ducommun B
Abstract excerpt
The effect of phleomycin, a bleomycin-like antibiotic, has been investigated in the fission yeast, Schizosaccharomyces pombe. We report that in response to phleomycin-induced DNA damage, growth was inhibited and S. pombe cells arrested in the G2-phase of the cell cycle. DNA repair mutants rad9 and rad17 did not arrest and were hypersensitive to phleomycin. Cell cycle mutants that entered mitosis without...
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