Article
Quiescent viral genomes in human fibroblasts after infection with herpes simplex virus type 1 Vmw65 mutants.
The Journal of general virology - 1 Jun 1995
Jamieson D R, Robinson L H, Daksis J I, Nicholl M J, Preston C M
Abstract excerpt
The development and utilization of a tissue culture system for the analysis of quiescent, nonreplicating herpes simplex virus type 1 (HSV-1) genomes is described. It was demonstrated previously that the HSV-1 Vmw65 mutant in1814, which is impaired for immediate early (IE) transcription, was retai...
Topics
- Cell Line
- DNA, Viral
- Enhancer Elements, Genetic
- Fetus
- Fibroblasts
- Gene Expression
- Genes, Immediate-Early
- Genome, Viral
- Genotype
- Herpes Simplex Virus Protein Vmw65
- Herpesvirus 1, Human
- Humans
- Interferon-alpha
- Kinetics
- Lung
- Plasmids
- Transcription, Genetic
- Transfection