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Article

Construction and characterization of a human cytomegalovirus mutant with the UL18 (class I homolog) gene deleted.

Journal of virology - 1 Nov 1992

Browne H, Churcher M, Minson T

Abstract excerpt

The UL18 open reading frame of human cytomegalovirus (HCMV) (which encodes a product homologous to major histocompatibility complex class I heavy chains) has been disrupted by insertion of the beta-galactosidase gene under control of the major HCMV early promoter. The recombinant virus delta UL18 showed no phenotypic differences from wild-type HCMV in terms of single-step growth curves or particle/infectivity...

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Identifiers

PMID: 1328689
DOI: 10.1128/JVI.66.11.6784-6787.1992
PMCID: PMC240178

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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