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Article

Biogenesis, structure and function of the yeast 20S proteasome.

The EMBO journal - 1 Jun 1995

Chen P, Hochstrasser M

Abstract excerpt

Intracellular degradation of many eukaryotic proteins requires their covalent ligation to ubiquitin. We previously identified a ubiquitin-dependent degradation pathway in the yeast Saccharomyces cerevisiae, the DOA pathway. Independent work has suggested that a major mechanism of cellular proteolysis involves a large multisubunit protease(s) called the 20S proteasome. We demonstrate here that Doa3 and Doa5, two...

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Identifiers

PMID: 7781614
DOI: 10.1002/j.1460-2075.1995.tb07260.x
PMCID: PMC398376

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Biogenesis, structure and function of the yeast 20S proteasome.PMID 7781614Read ↗

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