Article
Biogenesis, structure and function of the yeast 20S proteasome.
The EMBO journal - 1 Jun 1995
Chen P, Hochstrasser M
Abstract excerpt
Intracellular degradation of many eukaryotic proteins requires their covalent ligation to ubiquitin. We previously identified a ubiquitin-dependent degradation pathway in the yeast Saccharomyces cerevisiae, the DOA pathway. Independent work has suggested that a major mechanism of cellular proteol...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Biological Evolution
- Conserved Sequence
- Cysteine Endopeptidases
- DNA, Fungal
- Enzyme Precursors
- Humans
- Mammals
- Molecular Sequence Data
- Molecular Structure
- Multienzyme Complexes
- Mutation
- Proteasome Endopeptidase Complex
- Protein Conformation
- Protein Processing, Post-Translational
- Saccharomyces cerevisiae