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Article

Analysis of the deubiquitinating enzymes of the yeast Saccharomyces cerevisiae.

Biological chemistry - 1 Jan 2000

Amerik A Y, Li S J, Hochstrasser M

Abstract excerpt

Attachment of proteins to ubiquitin is reversed by specialized proteases called deubiquitinating enzymes (Dubs), which are also essential for ubiquitin precursor processing. In the genome of Saccharomyces cerevisiae, 17 potential DUB genes can be discerned. We have now constructed strains deleted for each of these genes. Surprisingly, given the essential nature of the ubiquitin system, none of the mutants is...

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Identifiers

PMID: 11076031
DOI: 10.1515/BC.2000.121

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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