Article
Mitochondrial Deoxyribonucleic Acid 4977-bp Deletion is Associated with Diminished Fertility and Motility of Human Sperm1
1 Apr 1995
Abstract excerpt
The accumulation of mitochondrial DNA (mtDNA) mutations has been suggested to be an important contributor to human aging and degenerative diseases. In previous studies, we found an age-dependent increase of mtDNA mutations in various human tissues. Sperm motility is one of the determinants of male fertility. The possible relationship between mtDNA deletions and diminished fertility and motility of sperm was...
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