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Article

Multiple deletions of mitochondrial DNA are associated with the decline of motility and fertility of human spermatozoa

1 Jul 1998

Abstract excerpt

Sperm motility is one of the major determinants of male fertility and is required for successful fertilization. In a previous study, we demonstrated that the occurrence and accumulation of the 4977 bp deletion of mitochondrial DNA (mtDNA) is associated with diminished fertility and motility of human spermatozoa. The possible relationship between multiple deletions of mtDNA and the decline of fertility and...

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PMID: 9701788
DOI: 10.1093/molehr/4.7.657

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