Article
Mitochondrial DNA content of human spermatozoa.
Biology of reproduction - 1 Jan 2003
Díez-Sánchez Carmen, Ruiz-Pesini Eduardo, Lapeña Ana Cristina, Montoya Julio, Pérez-Martos Acisclo, Enríquez José Antonio, López-Pérez Manuel J
Abstract excerpt
Sperm mitochondria play an important role in spermatozoa because of the high ATP demand of these cells. Different mitochondrial DNA (mtDNA) mutations and haplogroups influence sperm function. The mtDNA dose also contributes to genetic variability and pathology in different tissues and organs, but nothing is known about its relevance in the performance of spermatozoa. We estimated the variability in mtDNA content...
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