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Sperm mitochondrial DNA deletion in Iranian infertiles with asthenozoospermia

30 Jun 2016

Abstract excerpt

Asthenozoospermia is an important cause of male infertility. The mutations in sperm mitochondrial DNA (mtDNA) result in either functionless or malfunctioning some proteins, subsequently affecting sperm motility leading to asthenozoospermia. The purpose of this study was to investigate sperm mtDNA 4,977-bp deletion in infertile men with low sperm motility/immotile spermatozoa compared to healthy subjects with high...

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PMID: 27362525
DOI: 10.1111/and.12627

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