4,977‐bp human mitochondrial DNA deletion is associated with asthenozoospermic infertility in Jordan

Abstract excerpt

Male infertility is commonly associated with sperm abnormalities including asthenozoospermia. The molecular basis of asthenozoospermia was linked to mitochondrial DNA (mtDNA) mutations. The 4,977-bp human mtDNA deletion is one of the most common mutations of spermatozoa and results in loss of about 33% of the mitochondrial genome. In this preliminary study, we aimed to investigate the presence of 4,977-bp mtDNA...

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• Share to Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
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