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Article

The puzzle of Hox genes.

The International journal of developmental biology - 1 Dec 1994

Carrasco A E, López S L

Abstract excerpt

During the last few years, the regionalization of the rostral-caudal axis has been extensively studied through treatments with RA and genetic manipulations of Hox-C genes. RA shifts several Hox expression boundaries rostrally, deletes anterior rhombomeres but expands the caudal ones, and induces homeotic transformations in the vertebral column. These phenotypes indicate that retinoids may act in a graded fashion...

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PMID: 7779679

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