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Article

Retinoic acid regulation of the somitogenesis clock

1 Jun 2007

Abstract excerpt

Retinoic acid (RA) is a signaling molecule synthesized from vitamin A that controls gene expression at the transcriptional level by functioning as a ligand for nuclear RA receptors. RA plays an essential role during embryonic development in higher animals by regulating key genes involved in pattern formation. RA is required for induction of several Hox genes involved in patterning of the hindbrain and spinal cord...

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PMID: 17600781
DOI: 10.1002/bdrc.20092

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