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Article

Increased frequency of the C4A*6 rare allele in rheumatic heart disease.

Scandinavian journal of rheumatology - 1 Jan 1995

de Messias I J, Cavalcanti E, Radominski S C

Abstract excerpt

The aim of the present investigation was to determine whether the alleles of the MHC class III complement proteins BF, C2 and C4 (C4A and C4B) could be markers for RHD in the Brazilian population. Forty-nine patients with chronic RHD were studied. The controls included 65 healthy unrelated individuals, matched with the patients according to sex, age and ethnical background. BF, C2, C4A and C4B allotypes were...

Topics

Adolescent
Adult
Alleles
Complement C4
Female
Humans
Male
Middle Aged
Rheumatic Heart Disease

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 7777829
DOI: 10.3109/03009749509099307

Genes

RHD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7777829-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Increased frequency of the C4A*6 rare allele in rheumatic heart disease.PMID 7777829Read ↗

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Polymorphism of the complement components in human pathology.Semantic proximity Read ↗

Association of MASP2 polymorphisms and protein levels with rheumatic fever and rheumatic heart disease.Semantic proximity Read ↗

Novel FCN2 Variants and Haplotypes are Associated with Rheumatic Heart Disease.Semantic proximity Read ↗

Ficolin-3 in rheumatic fever and rheumatic heart disease.Semantic proximity Read ↗

Molecular genetics of the human MHC complement gene cluster.Semantic proximity Read ↗

Improved method for the allelic definition of C4A and C4B polymorphism (HLA class III).Semantic proximity Read ↗

Genetic variability of the MHC class III complement proteins C2, BF, C4A and C4B in southern Brazil.Semantic proximity Read ↗

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