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Article

A screen for RAS mutations in individuals at risk of secondary leukaemia due to occupational exposure to petrochemicals.

Leukemia research - 1 May 1995

Taylor C, Hughes D C, Zappone E, Cazzola M, Carter G, Jacobs A, Padua R A

Abstract excerpt

Occupational exposure to petrochemicals, in particular benzene, has been identified as a risk factor in the development of acute leukaemia. A cohort of exposed (n = 44) and non-exposed individuals (n = 19) from the same petrochemical installation were screened by polymerase chain reaction (PCR) followed by oligonucleotide hybridization (ONH) for the presence of mutations in the H, K, and NRAS cellular...

Topics

Adult
Benzene
Genes, ras
Humans
Leukemia
Mutation
Occupational Diseases
Oligonucleotide Probes
Oncogenes
Petroleum

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 7769829
DOI: 10.1016/0145-2126(95)00005-9

Genes

KRAS
NRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7769829-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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