Article
A screen for RAS mutations in individuals at risk of secondary leukaemia due to occupational exposure to petrochemicals.
Leukemia research - 1 May 1995
Taylor C, Hughes D C, Zappone E, Cazzola M, Carter G, Jacobs A, Padua R A
Abstract excerpt
Occupational exposure to petrochemicals, in particular benzene, has been identified as a risk factor in the development of acute leukaemia. A cohort of exposed (n = 44) and non-exposed individuals (n = 19) from the same petrochemical installation were screened by polymerase chain reaction (PCR) followed by oligonucleotide hybridization (ONH) for the presence of mutations in the H, K, and NRAS cellular...
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