Article
Bcl-2 protooncogene expression in cervical carcinoma cell lines containing inactive p53.
Journal of cellular biochemistry - 1 Mar 1995
Liang X H, Mungal S, Ayscue A, Meissner J D, Wodnicki P, Hockenbery D, Lockett S, Herman B
Abstract excerpt
Bcl-2 protein expression has been found to block apoptosis and its overexpression has been implicated in lymphoid malignancies where the chromosomal translocation t(14;18) is present. In this study we investigated bcl-2 transcription and protein expression in cultured cervical carcinoma cell lines and keratinocytes. Western blotting and immunofluorescence microscopy demonstrated bcl-2 expression in the cytoplasm...
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