Article
Expression pattern of AP-2 transcription factors in cervical cancer cells and analysis of their influence on human papillomavirus oncogene transcription.
Journal of molecular medicine (Berlin, Germany) - 1 Jun 2001
Beger M, Butz K, Denk C, Williams T, Hurst H C, Hoppe-Seyler F
Abstract excerpt
The AP-2 family of transcription factors consists of three known members, namely AP-2alpha, AP-2beta, and AP-2gamma. In experimental systems AP-2 factors possess tumor suppressor-like activities, and alterations in the AP-2 expression pattern have been described for some tumor entities. In addition, AP-2 has been implicated in the transcriptional control of human papillomaviruses (HPVs). We investigated here the...
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