Article
Domains of the human androgen receptor and glucocorticoid receptor involved in binding to the nuclear matrix.
Journal of cellular biochemistry - 1 Mar 1995
van Steensel B, Jenster G, Damm K, Brinkmann A O, van Driel R
Abstract excerpt
Steroid receptors have been reported to bind to the nuclear matrix. The nuclear matrix is operationally defined as the residual nuclear structure that remains after extraction of most of the chromatin and all soluble and loosely bound components. To obtain insight in the molecular mechanism of the interaction of steroid receptors with the nuclear matrix, we studied the binding of several deletion mutants of the...
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