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Article

Ligand Binding Prolongs Androgen Receptor Protein Half-Life by Reducing its Degradation

5 Mar 2021

Abstract excerpt

Abstract Androgens are important in female reproduction, but the molecular actions of androgens in female reproductive tissues are not fully understood. We investigated the androgen-responsive transcriptome in human and mouse granulosa cells (GCs) and surprisingly found that the gene-regulation activity of androgen receptor (AR) in these cells is negligible. We then investigated extranuclear actions of AR and...

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Share to Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
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PMID: 33869982
DOI: 10.1210/jendso/bvab035

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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