Increase caused by interleukin-6 in promoter activity of guinea pig liver transglutaminase gene.

doi:10.1271/bbb.58.1540

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Article

Increase caused by interleukin-6 in promoter activity of guinea pig liver transglutaminase gene.

Bioscience, biotechnology, and biochemistry - 1 Aug 1994

Ikura K, Shinagawa R, Suto N, Sasaki R

Abstract excerpt

A 5'-flanking region (-2024 to +61) of the guinea pig liver transglutaminase gene and some 5'-deletion mutants were tested for promoter activity in human hepatoblastoma HepG2 cells treated with interleukin-6 (IL-6) by an assay of the transient expression of the chloramphenicol acetyltransferase r...

Topics

Animals
Genes, Reporter
Guinea Pigs
Hepatoblastoma
Humans
Interleukin-6
Liver
Liver Neoplasms
Mutation
Promoter Regions, Genetic
TATA Box
Transglutaminases
Tumor Cells, Cultured

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