Article
Nuclear proteins bind a cis-acting element in the smooth muscle alpha-actin promoter.
The American journal of physiology - 1 May 1995
McNamara C A, Thompson M M, Vernon S M, Shimizu R T, Blank R S, Owens G K
Abstract excerpt
Identification of the regulators of smooth muscle cell (SMC) gene expression is critical to understanding SMC differentiation and alterations in SMC phenotype in vascular disease. Previous studies revealed positive transcriptional activity within the chicken smooth muscle (SM) alpha-actin promoter region from -209 to -257. In the present study, transient transfections of wild-type and mutant chicken SM...
Topics
- Actins
- Animals
- Aorta
- Base Sequence
- Binding Sites
- Cattle
- Consensus Sequence
- Endothelium, Vascular
- Molecular Probes
- Molecular Sequence Data
- Muscle, Smooth, Vascular