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Article

T Helper Cell Subsets in Insulin-Dependent Diabetes

26 May 1995

Abstract excerpt

It has been proposed that the development of insulin-dependent diabetes is controlled by the T helper 1 (TH1) versus TH2 phenotype of autoreactive TH cells: TH1 cells would promote diabetes, whereas TH2 cells would actually protect from disease. This proposition was tested by establishing cultures of TH1 and TH2 cells that express an identical diabetogenic T cell receptor and comparing their ability to initiate...

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PMID: 7761837
DOI: 10.1126/science.7761837

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