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Article

Insulin and the prevention of insulin-dependent diabetes mellitus.

Diabetes & metabolism - 1 Sept 1997

Coutant R, Carel J C, Timsit J, Boitard C, Bougnères P

Abstract excerpt

Insulin deficiency due to autoimmune destruction of pancreatic beta cells (insulin is an autoantigen) is responsible for insulin-dependent diabetes mellitus. Since 1923, substitutive administration of insulin has been used to treat the disease. Surprisingly, initial usage of insulin is associated with partial resumption of insulin secretion in most patients. This phenomenon is intensified by aggressive insulin...

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Source

Identifiers

PMID: 9342539

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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