Article
Insulin and the prevention of insulin-dependent diabetes mellitus.
Diabetes & metabolism - 1 Sept 1997
Coutant R, Carel J C, Timsit J, Boitard C, Bougnères P
Abstract excerpt
Insulin deficiency due to autoimmune destruction of pancreatic beta cells (insulin is an autoantigen) is responsible for insulin-dependent diabetes mellitus. Since 1923, substitutive administration of insulin has been used to treat the disease. Surprisingly, initial usage of insulin is associated...
Topics
- Animals
- Autoantigens
- B-Lymphocytes
- Chromosome Mapping
- Clinical Trials as Topic
- Diabetes Mellitus, Type 1
- Genetic Predisposition to Disease
- Humans
- Injections, Subcutaneous
- Insulin