Article
L-selectin(-/lo) and diabetogenic T cells are similarly distributed in prediabetic and diabetic nonobese diabetic mice.
Laboratory investigation; a journal of technical methods and pathology - 1 May 1998
Lepault F, Gagnerault M C
Abstract excerpt
We have previously shown that in the nonobese diabetic (NOD) mouse, an experimental model for autoimmune insulin-dependent diabetes, spleen diabetogenic T cells are contained within the T-cell subpopulation that express no or low levels of L-selectin. This phenotype characterizes activated/memory T cells. In the present study, we have compared the distribution of autoreactive T cells to that of L-selectin -/lo T...
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