A weak association between TH and DRD2 genes and bipolar affective disorder in a Spanish sample.

doi:10.1136/jmg.32.2.131

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Article

A weak association between TH and DRD2 genes and bipolar affective disorder in a Spanish sample.

Journal of medical genetics - 1 Feb 1995

Pérez de Castro I, Santos J, Torres P, Visedo G, Saiz-Ruiz J, Llinares C, Fernández-Piqueras J

Abstract excerpt

Genetic factors play an important role in the aetiology of bipolar affective disorder (BP). So far, results of linkage studies have been largely disappointing. We have searched for a possible association between polymorphic DNA markers of two candidate genes (tyrosine hydroxylase, TH; dopamine D2...

Topics

Adult
Alleles
Bipolar Disorder
Case-Control Studies
Female
Gene Frequency
Genetic Linkage
Genetic Markers
Genetics, Population
Genotype
Humans
Male
Middle Aged
Pedigree
Polymorphism, Genetic
Receptors, Dopamine D2
Repetitive Sequences, Nucleic Acid
Spain

Source

Open in PubMed Open full text

Identifiers

PMID: 7760324
DOI: 10.1136/jmg.32.2.131
PMCID: PMC1050236

Genes

DRD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7760324-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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