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Article

Strain differences in the laboratory rat: impact on the autonomic, behavioral, and biochemical response to cholinesterase inhibition.

Journal of toxicology and environmental health - 1 May 1995

Gordon C J, Watkinson W P

Abstract excerpt

Intraspecies variation has been found to affect the physiological, behavioral, and biochemical responses to a variety of neurotoxicants, including the organophosphate diisopropyl fluorophosphate (DFP). However, there is little information on long-term physiological responses to neurotoxicant exposure using strain as a dependent variable. In the present study, radiotelemetry methodology was used to continuously...

Topics

Analysis of Variance
Animals
Body Temperature
Brain
Cholinesterases
Genetic Variation
Heart Rate
Injections, Subcutaneous
Isoflurophate
Male
Motor Activity

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Rats

Rats, Inbred F344

Rats, Sprague-Dawley

Rats, Wistar

Species Specificity

Source

Identifiers

PMID: 7752289
DOI: 10.1080/15287399509531980

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7752289-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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