A POU homeo domain protein related to dPOU-19/pdm-1 binds to the regulatory DNA necessary for vital expression of the Drosophila choline acetyltransferase gene.

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Article

A POU homeo domain protein related to dPOU-19/pdm-1 binds to the regulatory DNA necessary for vital expression of the Drosophila choline acetyltransferase gene.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 1 May 1995

Kitamoto T, Salvaterra P M

Abstract excerpt

Expression of the choline acetyltransferase (ChAT) gene in Drosophila melanogaster is responsible for production of the neurotransmitter acetylcholine and is necessary for viability. In previous studies, we have shown that the regulatory region for normal ChAT expression is large and composed of multiple regulatory elements (Kitamoto et al., 1992; Kitamoto and Salvaterra, 1993). In this study, using various...

Topics

Animals
Animals, Genetically Modified
Base Sequence
Binding Sites
Choline O-Acetyltransferase
Chromosome Mapping
Consensus Sequence
DNA
DNA-Binding Proteins
Drosophila Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Drosophila melanogaster

Embryo, Nonmammalian

Gene Expression Regulation, Enzymologic

Genes, Insect

Genes, Lethal

Genetic Linkage

Homeodomain Proteins

Immunoblotting

Source

Open in PubMed Open full text

Identifiers

PMID: 7751926
PMCID: PMC6578218

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7751926-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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