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Article

Optimisation and properties of a UHG for genotyping of hemoglobins S and C.

Human mutation - 1 Jan 1995

Wood N, Standen G, Old J, Bidwell J

Abstract excerpt

The use of universal heteroduplex generators (UHG) as an effective means of screening for specific mutations has been previously reported. Here, we report the optimisation of a UHG system used for the rapid and simple detection of sickle cell hemoglobinopathies, HbS and HbC. The test involves heteroduplex formation between between polymerase chain reaction (PCR)-amplified beta-globin gene first exon sequences,...

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Identifiers

PMID: 7749414
DOI: 10.1002/humu.1380050210

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CAT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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