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Article

The central role of CDE/CHR promoter elements in the regulation of cell cycle‐dependent gene transcription

15 Dec 2009

Abstract excerpt

The cell cycle-dependent element (CDE) and the cell cycle genes homology region (CHR) control the transcription of genes with maximum expression in G(2) phase and in mitosis. Promoters of these genes are repressed by proteins binding to CDE/CHR elements in G(0) and G(1) phases. Relief from repression begins in S phase and continues into G(2) phase and mitosis. Generally, CDE sites are located four nucleotides...

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PMID: 20015071
DOI: 10.1111/j.1742-4658.2009.07508.x

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