Article
Cyclin-dependent kinase activation and S-phase induction of the cyclin B1 gene are linked through the CCAAT elements.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research - 1 Jul 1997
Katula K S, Wright K L, Paul H, Surman D R, Nuckolls F J, Smith J W, Ting J P, Yates J, Cogswell J P
Abstract excerpt
Control of cell proliferation is dependent on the regulated expression of the cyclin genes. Induction of cyclin B1 gene expression in S phase has been shown to require sequences within the first 90 bp of the proximal promoter region. In this study, we defined the cell cycle regulatory elements wi...
Topics
- 3T3 Cells
- Animals
- Base Sequence
- CCAAT-Enhancer-Binding Proteins
- CDC2-CDC28 Kinases
- Cyclin B
- Cyclin B1
- Cyclin-Dependent Kinase 2
- Cyclin-Dependent Kinase 4
- Cyclin-Dependent Kinases
- Cyclins
- DNA-Binding Proteins
- HeLa Cells
- Humans