Article
Role of charge in the radioprotection of E. coli by thiols.
International journal of radiation biology - 1 Apr 1995
Prise K M, Gillies N E, Whelan A, Newton G L, Fahey R C, Michael B D
Abstract excerpt
The role of net charge (zeta) of thiols in their ability to radioprotect cells has been investigated in a glutathione (GSH)-deficient strain of E. coli. This strain, 7, is deficient in the enzyme gamma-glutamylcysteine synthetase and allows the effects of added low molecular weight thiols to be s...
Topics
- DNA Repair
- DNA, Bacterial
- Dose-Response Relationship, Radiation
- Escherichia coli
- Free Radicals
- Glutathione
- Mutation
- Oxygen
- Radiation Tolerance
- Sulfhydryl Compounds
- Time Factors