Article
Role of charge in the radioprotection of E. coli by thiols.
International journal of radiation biology - 1 Apr 1995
Prise K M, Gillies N E, Whelan A, Newton G L, Fahey R C, Michael B D
Abstract excerpt
The role of net charge (zeta) of thiols in their ability to radioprotect cells has been investigated in a glutathione (GSH)-deficient strain of E. coli. This strain, 7, is deficient in the enzyme gamma-glutamylcysteine synthetase and allows the effects of added low molecular weight thiols to be studied. Using the gas explosion system it is possible to measure the chemical repair of the free-radical precursors of...
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