Article
Glutathione is a target in tellurite toxicity and is protected by tellurite resistance determinants in Escherichia coli.
Canadian journal of microbiology - 1 Jan 2001
Turner R J, Aharonowitz Y, Weiner J H, Taylor D E
Abstract excerpt
Tellurite (TeO3(2-)) is highly toxic to most microorganisms. The mechanisms of toxicity or resistance are poorly understood. It has been shown that tellurite rapidly depletes the reduced thiol content within wild-type Escherichia coli. We have shown that the presence of plasmid-borne tellurite-resistance determinants protects against general thiol oxidation by tellurite. In the present study we observe that the...
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