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Article

The "pro-drug" RibCys decreases the mutagenicity of high-LET radiation in cultured mammalian cells.

Radiation research - 1 Nov 2003

Lenarczyk M, Ueno A, Vannais D B, Kraemer S, Kronenberg A, Roberts J C, Tatsumi K, Hei T K, Waldren C A

Abstract excerpt

We are carrying out studies aimed at reducing the mutagenic effects of high-LET 56Fe ions and 12C ions (56Fe ions, 143 keV/microm; 12C ions, 100 keV/microm) with certain drugs, including RibCys [2-(R,S)-D-ribo-(1',2',3',4'-tetrahydroxybutyl)-thiazolidine-4(R)-carboxylic acid]. RibCys, formed by c...

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Identifiers

PMID: 14565824
DOI: 10.1667/3065

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-14565824-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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