Article
Cells with UV-specific DNA damage are present in murine lymph nodes after in vivo UV irradiation.
The Journal of investigative dermatology - 1 May 1995
Sontag Y, Guikers C L, Vink A A, de Gruijl F R, van Loveren H, Garssen J, Roza L, Kripke M L, van der Leun J C, van Vloten W A
Abstract excerpt
Ultraviolet radiation is absorbed in the skin, especially in the epidermis. After ultraviolet irradiation the number of major histocompatibility complex class II+, adenosine triphosphatase+ Langerhans cells and Thy-1+ dendritic epidermal cells in the epidermis decreases. Whether this decrease is due to migration of these cells or to loss of membrane markers is not clear. To address this question we have used the...
Topics
- Animals
- Cell Movement
- DNA Damage
- Female
- Lymph Nodes
- Mice
- Mice, Inbred Strains
- Phenotype
- Pyrimidine Dimers
- Ultraviolet Rays