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Article

Ultraviolet B suppresses immunity by inhibiting effector and memory T cells.

The American journal of pathology - 1 Apr 2008

Rana Sabita, Byrne Scott Napier, MacDonald Linda Joanne, Chan Carling Yan-Yan, Halliday Gary Mark

Abstract excerpt

Contact hypersensitivity is a T-cell-mediated response to a hapten. Exposing C57BL/6 mice to UV B radiation systemically suppresses both primary and secondary contact hypersensitivity responses. The effects of UVB on in vivo T-cell responses during UVB-induced immunosuppression are unknown. We show here that UVB exposure, before contact sensitization, inhibits the expansion of effector CD4+ and CD8+ T cells in...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 18292235
DOI: 10.2353/ajpath.2008.070517
PMCID: PMC2276424

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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