Article
Thymus-independent generation of Thy-1+ epidermal cells from a pool of Thy-1- bone marrow precursors.
The Journal of investigative dermatology - 1 Nov 1990
Honjo M, Elbe A, Steiner G, Assmann I, Wolff K, Stingl G
Abstract excerpt
Thy-1+ dendritic epidermal cells (Thy-1+ DEC) and immature thymocytes share several phenotypic features: CD45+, Thy-1+, asialo-GM1+, CD3+, CD4-, and CD8-. In view of this similarity, it has been suggested that the epidermis may be a site of either post-thymic or extra-thymic T-cell development. I...
Topics
- Animals
- Antigens, Differentiation, T-Lymphocyte
- Antigens, Surface
- Antigens, T-Independent
- Bone Marrow
- Bone Marrow Cells
- CD3 Complex
- Chimera
- Epidermal Cells
- Epidermis
- Hematopoietic Stem Cells
- Male
- Mice
- Phenotype
- Receptors, Antigen, T-Cell
- Receptors, Lymphocyte Homing
- T-Lymphocytes
- Thy-1 Antigens