Article
Thymus-independent generation of Thy-1+ epidermal cells from a pool of Thy-1- bone marrow precursors.
The Journal of investigative dermatology - 1 Nov 1990
Honjo M, Elbe A, Steiner G, Assmann I, Wolff K, Stingl G
Abstract excerpt
Thy-1+ dendritic epidermal cells (Thy-1+ DEC) and immature thymocytes share several phenotypic features: CD45+, Thy-1+, asialo-GM1+, CD3+, CD4-, and CD8-. In view of this similarity, it has been suggested that the epidermis may be a site of either post-thymic or extra-thymic T-cell development. In order to address this issue, we used C3H/He/Han (Thy-1.2)----AKR/Ola (Thy-1.1) radiation bone marrow chimeras....
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