Article
Human somatic mutation assays as biomarkers of carcinogenesis.
Environmental health perspectives - 1 Aug 1991
Compton P J, Hooper K, Smith M T
Abstract excerpt
This paper describes four assays that detect somatic gene mutations in humans: the hypoxanthine-guanine phosphoribosyl transferase assay, the glycophorin A assay, the HLA-A assay, and the sickle cell hemoglobin assay. Somatic gene mutation can be considered a biomarker of carcinogenesis, and assays for somatic mutation may assist epidemiologists in studies that attempt to identify factors associated with...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
